Abstract: Objective To investigate the effect of accelerated rehabilitation surgery on early postoperative cognitive function protection in patients with refractory epilepsy.How:Forty patients with drug-resistant epilepsy diagnosed and treated in our hospital from January 2020 to December 2021 were selected,all of whom underwent anterior temporal lobotomy,and the surgical side was all on the right side.They were divided into the observation group and the control group with 20 patients in each group according to random number. Methods The observation group received perioperative accelerated rehabilitation surgery,while the control group received perioperative routine treatment.The changes of cognitive function,quality of life,hospitalization cost and length of stay were compared before and after operation. Results The observation group was superior to the control group in terms of cognitive function indexes such as the simple intelligence status checklist,Wechsler adult memory Scale,intelligence scale and quality of life scale,and the difference was statistically significant (P<0.05).The observation group had less time to eat,get out of bed,hospital expenses,urinary tube removal time and hospital stay in the early postoperative period than the control group.The difference was statistically significant (P<0.05). Conclusion The application of accelerated rehabilitation surgery in the perioperative period of anterior temporal lobectomy in patients with refractory epilepsy can reduce the risk of cognitive dysfunction,improve the quality of life of patients,accelerate their rehabilitation,and reduce the medical cost of patients.

Key words: Accelerated rehabilitation surgery, Drug refractory epilepsy, Anterior temporal lobectomy, Cognitive dysfunction

摘要： 目的 探讨采用加速康复外科对难治性癫痫患者术后早期认知功能保护的应用疗效。方法 选取2020年1月～2021年12月在我院诊治的药物难治性癫痫患者40例,均行前颞叶切除术,手术侧别均为右侧,按照随机数字法分为观察组与对照组各20例患者,观察组围术期采取加速康复外科手段,对照组围术期行常规治疗,观察2组患者手术前后的认知功能变化、比较生活质量、住院费用、住院时间等临床指标。结果 观察组术后简易智能状态检查量表、韦氏成人记忆量表、智力量表等认知功能指标及生活质量量表均优于对照组,差异有统计学意义(P＜0.05),观察组术后早期进食时间、下床活动时间、住院费用、尿管拔除时间、住院时间均少于对照组,差异有统计学意义(P＜0.05)。结论 在难治性癫痫患者行前颞叶切除围术期应用加速康复外科能减少发生认知功能障碍风险,同时能改善患者生活质量,加速其康复,减轻患者医疗成本。

关键词: 加速康复外科, 药物难治性癫痫, 前颞叶切除术, 认知功能障碍