doi:10.19854/j.cnki.1008-2425.2023.04.0012

Abstract

摘要： 立体定向脑电图(SEEG)不仅作为侵入性颅内脑电波监测手段,其引导下多电极立体交叉射频热凝损毁(RF-TC)也是一种安全、精准、高效的治愈性治疗手段,其独特优势可作为传统手术切除致痫灶的重要补充治疗手段,有望在未来的癫痫外科领域广泛应用。本文通过文献综述,简述多电极立体交叉SEEG-RF-TC在药物难治性癫痫(DRE)术前评估、安全性、有效性中的应用,并提出对其未来进一步研究的展望。

关键词: SEEG, 三维, RF-TC, 药物难治性癫痫

CLC Number:

R742.1

王中鸣, 王琴, 彭琼, 黄亚辉, 李振光, 卢军. SEEG 引导下多电极立体交叉射频热凝损毁治疗药物难治性癫痫的研究进展[J]. 立体定向和功能性神经外科杂志, 2023, 36(4): 250-256.

References

[1] Beghi E.The epidemiology of epilepsy[J].Neuroepidemiology,2020,54(2):185~191.
[2] Margineanu DG,Klitgaard H.Mechanisms of drug resistance in epilepsy:relevance for antiepileptic drug discovery[J].Expert Opinion on Drug Discovery,2009,4(1):23~32.
[3] Lasoń W.The prospects for genomics and proteomics in epilepsy[J].American Journal of Case Reports,2008,16(3):207~216.
[4] Jacobs MP,Leblanc GG,Brooks-Kayal A,et al.Curing epilepsy:progress and future directions[J].Epilepsy & Behavior,2009,14(3):438~445.
[5] 沈雁文,邹丽萍.从精准医疗的角度看药物难治性癫痫[J].解放军医学院学报,2019,40(3):282~285.
[6] Behr C,Goltzene MA,Kosmalski G,et al.Epidemiology of epilepsy[J].Revue neurologique,2016,172(1):27~36.
[7] Ding D,Zhou D,Sander JW,et al.Epilepsy in China:major progress in the past two decades[J].The Lancet Neurology,2021,20(4):316~326.
[8] Trinka E,Kwan P,Lee BI,et al.Epilepsy in Asia:disease burden,management barriers,and challenges[J].Epilepsia,2019,60:7~21.
[9] Song P,Liu Y,Yu X,et al.Prevalence of epilepsy in China between 1990 and 2015:a systematic review and meta-analysis[J].Journal of global health,2017,7(2).
[10] Tong X,Chen J,Park SP,et al.Social support for people with epilepsy in China[J].Epilepsy & Behavior,2016,64:224~232.
[11] Chen Z,Brodie MJ,Liew D,et al.Treatment outcomes in patients with newly diagnosed epilepsy treated with established and new antiepileptic drugs:a 30-year longitudinal cohort study[J].JAMA neurology,2018,75(3):279~286.
[12] Schmidt D,Löscher W.New developments in antiepileptic drug resistance:an integrative view[J].Epilepsy Currents,2009,9(2):47~52.
[13] Park KM,Kim SE,Lee BI.Antiepileptic drug therapy in patients with drug-resistant epilepsy[J].Journal of epilepsy research,2019,9(1):14.
[14] 沈雁文,石秀玉,邹丽萍.癫痫治疗的机制研究新进展[J].解放军医学院学报,2020,41(12):1240~1246.
[15] Shankar R,Rowe C,Van Hoorn A,et al.Under representation of people with epilepsy and intellectual disability in research[J].PLoS One,2018,13(6):e0198261.
[16] Spiciarich MC,von Gaudecker JR,Jurasek L,et al.Global health and epilepsy:update and future directions[J].Current neurology and neuroscience reports,2019,19(6):1~8.
[17] Kanmounye US,Angelov L,Pannullo SC,et al.The role of neurosurgery in global health epilepsy,movement disorders,and psychiatric diseases[M] //Neurosurgery and Global Health.Springer,Cham,2022:107~122.
[18] Fiest KM,Sajobi TT,Wiebe S.Epilepsy surgery and meaningful improvements in quality of life:results from a randomized controlled trial[J].Epilepsia,2014,55(6):886~892.
[19] Sperling MR,Barshow S,Nei M,et al.A reappraisal of mortality after epilepsy surgery[J].Neurology,2016,86(21):1938~1944.
[20] Picot MC,Jaussent A,Neveu D,et al.Cost-effectiveness analysis of epilepsy surgery in a controlled cohort of adult patients with intractable partial epilepsy:A 5-year follow-up study[J].Epilepsia,2016,57(10):1669~1679.
[21] Langfitt JT,Holloway RG,McDermott MP,et al.Health care costs decline after successful epilepsy surgery[J].Neurology,2007,68(16):1290~1298.
[22] Chugani HT,Ilyas M,Kumar A,et al.Surgical treatment for refractory epileptic spasms:the Detroit series[J].Epilepsia,2015,56(12):1941~1949.
[23] Althausen A,Gleissner U,Hoppe C,et al.Long-term outcome of hemispheric surgery at different ages in 61 epilepsy patients[J].Journal of Neurology,Neurosurgery & Psychiatry,2013,84(5):529~536.
[24] Bourdillon P,Isnard J,Catenoix H,et al.Stereo electroencephalography-guided radiofrequency thermocoagulation (SEEG-guided RF-TC) in drug-resistant focal epilepsy:Results from a 10-year experience[J].Epilepsia,2017,58(1):85~93.
[25] Moles A,Guénot M,Rheims S,et al.SEEG-guided radiofrequency coagulation (SEEG-guided RF-TC) versus anterior temporal lobectomy (ATL) in temporal lobe epilepsy[J].Journal of Neurology,2018,265(9):1998~2004.
[26] Gao R,Yu T,Xu C,et al.The value of magnetoencephalography for stereo-EEG-guided radiofrequency thermocoagulation in MRI-negative epilepsy[J].Epilepsy Research,2020,163:106322.
[27] Bai J,Zhou W,Wang H,et al.Value of stereoelectroencephalography (SEEG)-guided radiofrequency thermocoagulation in treating drug-resistant focal epilepsy[J].Brain Science Advances,2019,5(3):189~202.
[28] Cossu M,Fuschillo D,Casaceli G,et al.Stereoelectroencephalography-guided radiofrequency thermocoagulation in the epileptogenic zone:a retrospective study on 89 cases[J].Journal of neurosurgery,2015,123(6):1358~1367.
[29] Wang L,Jin W,Zhang Y,et al.Stereoelectroencephalography-guided radiofrequency thermocoagulation in drug-resistant focal epilepsy[J].Annals of Translational Medicine,2022,10(4).
[30] Sarikaya I.PET studies in epilepsy[J].American journal of nuclear medicine and molecular imaging,2015,5(5):416.
[31] Rüber T,David B,Elger CE.MRI in epilepsy:clinical standard and evolution[J].Current opinion in neurology,2018,31(2):223~231.
[32] Strambo D,Rey V,Rossetti AO,et al.Perfusion-CT imaging in epileptic seizures[J].Journal of neurology,2018,265(12):2972~2979.
[33] 王玲,柳江燕,任婉娜.PET-CT和PET-MRI在药物难治性癫痫中的研究进展[J].癫痫杂志,2021,7(3):257~261.
[34] 赵瑞,周渊峰,杨皓玮,等.基于多模态影像的立体定向脑电图在儿童难治性癫痫治疗中的应用[J].中华神经外科杂志,2018,34(9):878~882.
[35] Guerin J,Watson RE,Carr CM,et al.Autoimmune epilepsy:findings on MRI and FDG-PET[J].The British Journal of Radiology,2019,92(1093):20170869.
[36] LoPinto-Khoury C,Sperling M R,Skidmore C,et al.Surgical outcome in PET-positive,MRI-negative patients with temporal lobe epilepsy[J].Epilepsia,2012,53(2):342~348.
[37] Salamon N,Kung J,Shaw SJ,et al.FDG-PET/MRI coregistration improves detection of cortical dysplasia in patients with epilepsy[J].Neurology,2008,71(20):1594~1601.
[38] Ramos-Fresnedo A,Domingo RA,McGeary RC,et al.Encephalocele-Associated Drug-Resistant Epilepsy of Adult Onset:Diagnosis,Management,and Outcomes[J].World neurosurgery,2021,151:91~101.
[39] 谭启富,陈谦学.积极稳妥地开展癫痫的外科治疗[J].临床外科杂志,2015,23(6):410~411.
[40] 王锴锁,姚晨,王圆庆,等.立体定向脑电图在癫痫术前评估与治疗中应用的研究进展[J].癫痫与神经电生理学杂志,2022,31(3):180-183.
[41] Khoo HM,Hall JA,Dubeau F,et al.Technical aspects of SEEG and its interpretation in the delineation of the epileptogenic zone[J].Neurologia medico-chirurgica,2020,60(12):565~580.
[42] Cossu M,Cardinale F,Castana L,et al.Stereoelectroencephalography in the presurgical evaluation of focal epilepsy:a retrospective analysis of 215 procedures[J].Neurosurgery,2005,57(4):706~718.
[43] 周健,翟锋,关宇光,等.机器人立体定向手术辅助系统辅助下的立体定向颅内电极置入精准定位致痫灶及切除[J].癫痫杂志,2016,2(4):290~295.
[44] Mullin JP,Shriver M,Alomar S,et al.Is SEEG safe? A systematic review and meta-analysis of stereo-electroencephalography-related complications[J].Epilepsia,2016,57(3):386~401.
[45] González-Martínez J,Bulacio J,Thompson S,et al.Technique,results,and complications related to robot-assisted stereoelectroencephalography[J].Neurosurgery,2016,78(2):169~180.
[46] Ollivier I,Behr C,Cebula H,et al.Efficacy and safety in frameless robot-assisted stereo-electroencephalography (SEEG) for drug-resistant epilepsy[J].Neurochirurgie,2017,63(4):286~290.
[47] 卢军.立体定向脑电图引导下射频热凝毁损术治疗药物难治性癫痫[J].实用心脑肺血管病杂志,2019,27(S2):78~80.
[48] Tandon N,Tong BA,Friedman ER,et al.Analysis of morbidity and outcomes associated with use of subdural grids vs stereoelectroencephalography in patients with intractable epilepsy[J].JAMA neurology,2019,76(6):672~681.
[49] Miller C,Schatmeyer B,Landazuri P,et al.sEEG for expansion of a surgical epilepsy program:Safety and efficacy in 152 consecutive cases[J].Epilepsia Open,2021,6(4):694~702.
[50] Goldstein HE,Youngerman BE,Shao B,et al.Safety and efficacy of stereoelectroencephalography in pediatric focal epilepsy:a single-center experience[J].Journal of Neurosurgery:Pediatrics,2018,22(4):444~452.
[51] Garcia-Lorenzo B,del Pino-Sedeño T,Rocamora R,et al.Stereoelectroencephalography for refractory epileptic patients considered for surgery:systematic review,meta-analysis,and economic evaluation[J].Neurosurgery,2019,84(2):326~338.
[52] Mullin JP,Smithason S,Gonzalez-Martinez J.Stereo-electro-encephalo-graphy (SEEG) with robotic assistance in the presurgical evaluation of medical refractory epilepsy:a technical note[J].JoVE (Journal of Visualized Experiments),2016 (112):e53206.
[53] Zheng J,Liu YL,Zhang D,et al.Robot-assisted versus stereotactic frame-based stereoelectroencephalography in medically refractory epilepsy[J].Neurophysiologie Clinique,2021,51(2):111~119.
[54] Kappen P,Eltze C,Tisdall M,et al.Stereo-EEG exploration in the insula/operculum in paediatric patients with refractory epilepsy[J].Seizure,2020,78:63~70.
[55] Lagarde S,Roehri N,Lambert I,et al.Interictal stereotactic-EEG functional connectivity in refractory focal epilepsies[J].Brain,2018,141(10):2966~2980.
[56] 徐成伟,周文静,柏建军,等.立体定向脑电图引导射频热凝在难治性颞叶癫痫中的应用[J].中华医学杂志,2018,98(13):1008~1012.
[57] 中国医师协会神经外科分会功能神经外科学组,中国抗癫痫协会,国家神经外科手术机器人应用示范项目专家指导委员会.立体定向脑电图引导射频热凝毁损治疗药物难治性癫痫的中国专家共识[J].中华医学杂志,2021,101(29):2276~2282.
[58] 胡峰,吴世强,康慧聪,等.立体定向脑电图在功能区难治性癫痫中的应用[J].临床外科杂志,2020,28(9):829~831.
[59] 田海港,郭效东,王本瀚,等.立体定向脑电图在MRI阴性难治性癫痫中的应用价值[J].临床神经外科杂志,2020,17(2):155~159.
[60] 贾建华,陈思,吴倩倩,等.立体定向脑电图引导下射频热凝毁损术治疗药物难治性癫痫的有效性分析[J].山东大学学报(医学版),2021,59(10):80~86.
[61] Fan X,Shan Y,Lu C,et al.Optimized SEEG-guided radiofrequency thermocoagulation for mesial temporal lobe epilepsy with hippocampal sclerosis[J].Seizure,2019,71:304~311.
[62] Dai Y,Wang YH,An Y,et al.Observation of efficacy and safety of stereotactic-EEG-guided three-dimensional radiofrequency thermocoagulation for the treatment of drug-resistant insular epilepsy[J].Zhonghua yi xue za zhi,2021,101(41):3386~3392.
[63] Wang L,Jin W,Zhang Y,et al.Stereoelectroencephalography-guided radiofrequency thermocoagulation in drug-resistant focal epilepsy[J].Annals of Translational Medicine,2022,10(4).
[64] Bourdillon P,Cucherat M,Isnard J,et al.Stereo-electroencephalography-guided radiofrequency thermocoagulation in patients with focal epilepsy:a systematic review and meta-analysis[J].Epilepsia,2018,59(12):2296~2304.
[65] Bourdillon P,Devaux B,Job-Chapron AS,et al.SEEG-guided radiofrequency thermocoagulation[J].Neurophysiologie Clinique,2018,48(1):59~64.
[66] Narasimhan S,Kundassery KB,Gupta K,et al.Seizure-onset regions demonstrate high inward directed connectivity during resting-state:An SEEG study in focal epilepsy[J].Epilepsia,2020,61(11):2534~2544.
[67] Bhusal B,Bhattacharyya P,Baig T,et al.Measurements and simulation of RF heating of implanted stereo-electroencephalography electrodes during MR scans[J].Magnetic resonance in medicine,2018,80(4):1676~1685.
[68] 张华强,李沐阳,杜佳琳,等.立体脑电图引导多电极立体交叉射频热凝治疗药物难治性癫痫[J].中华神经外科杂志,2018,34(12):1197~1201.
[69] Wei PH,Fan XT,Wang YH,et al.Stereo-crossed ablation guided by stereoelectroencephalography for epilepsy:comprehensive coagulations via a network of multi-electrodes[J].Therapeutic Advances in Neurological Disorders,2020,13:1756286420928657.
[70] 戴阳,王逸鹤,安阳,等.立体定向脑电图引导下立体交叉射频热凝毁损治疗药物难治性岛叶癫痫的安全性及有效性观察[J].中华医学杂志,2021,101(41):3386~3392.
[71] Stelzle D,Kaducu J,Schmidt V,et al.Characteristics of people with epilepsy in three Eastern African countries-a pooled analysis[J].BMC neurology,2022,22(1):1~12.
[72] Ho AL,Muftuoglu Y,Pendharkar AV,et al.Robot-guided pediatric stereoelectroencephalography:single-institution experience[J].Journal of Neurosurgery:Pediatrics,2018,22(5):489~496.
[73] Mirza FA,Hall JA.Radiofrequency Thermocoagulation in Refractory Focal Epilepsy:The Montreal Neurological Institute Experience[J].Canadian Journal of Neurological Sciences,2021,48(5):626~639.
[74] 王慧杰,袁冠前,黄平,等.局部麻醉下ROSA机器人辅助SEEG电极植入的精准性与安全性分析[J].中华神经外科杂志,2020(4):361~364.
[75] Leonardi M,Ustun TB.The global burden of epilepsy[J].Epilepsia,2002,43:21~25.
[76] Specchio N,Pavia GC,de Palma L,et al.Current role of surgery for tuberous sclerosis complex-associated epilepsy[J].Pediatric Investigation,2022,6(1):16~22.
[77] Yan XM,Xu CP,Wang YP,et al.A study of medial and lateral temporal lobe epilepsy based on stereoelectroencephalography[J].Chinese Medical Journal,2021,134(1):68~72.
[78] Yoon S,Goh H,Foo CP,et al.Parents’ priorities for decision-making of pediatric epilepsy treatments and perceived needs for decision support in multi-ethnic Asian clinical setting:A qualitative analysis[J].Epilepsy & Behavior,2022,135:108880.
[79] Cossu M,Cardinale F,Casaceli G,et al.Stereo-EEG-guided radiofrequency thermocoagulations[J].Epilepsia,2017,58:66~72.
[80] Bouthillier A,Nguyen DK.Epilepsy surgeries requiring an operculoinsular cortectomy:operative technique and results[J].Neurosurgery,2017,81(4):602~612.
[81] Fernandes DA,Yasuda CL,Lopes TM,et al.Long-term postoperative atrophy of contralateral hippocampus and cognitive function in unilateral refractory MTLE with unilateral hippocampal sclerosis[J].Epilepsy & Behavior,2014,36:108~114.
[82] Lee CY,Li HT,Wu T,Cheng MY,Lim SN,Lee ST.Efficacy of limited hippocampal radiofrequency thermocoagulation for mesial temporal lobe epilepsy[J].J Neurosurg,2018;131(3):781~789.

SEEG 引导下多电极立体交叉射频热凝损毁治疗药物难治性癫痫的研究进展

PDF

Knowledge

Abstract

Cite this article

share this article

References

Related Articles 15

Recommended Articles

Metrics

Comments

[1]	Liu Qian, Jiao Men, Yao Dongxu, et al. Functional brain network characteristics of preemptive analgesia with dexmetomidine under intraoperative fMRI [J]. Chinese Journal of Stereotactic and Functional Neurosurgery, 2023, 36(5): 257-261.
[2]	. [J]. Chinese Journal of Stereotactic and Functional Neurosurgery, 2023, 36(5): 316-320.
[3]	Cao Hui, Zhou Min, Shu Yunyun, et al. Protective effect and mechanism of Tanshinone ⅡA on hippocampal neuron injury in epileptic mice [J]. Chinese Journal of Stereotactic and Functional Neurosurgery, 2023, 36(4): 205-212.
[4]	Li Huanfa, Liu Yong, Meng Qiang, et al. Long-term outcome of reoperation following resective surgery for refractory epilepsy [J]. Chinese Journal of Stereotactic and Functional Neurosurgery, 2023, 36(4): 213-216.
[5]	Shi Xianjun, Sun Xiaoqin, Feng lin, et al. Surgical treatment of rolandic intractable epilepsy [J]. Chinese Journal of Stereotactic and Functional Neurosurgery, 2023, 36(3): 129-134.
[6]	. [J]. Chinese Journal of Stereotactic and Functional Neurosurgery, 2023, 36(3): 186-192.
[7]	. Surgical treatment of older patients with epilepsy:report of 22 cases [J]. Chinese Journal of Stereotactic and Functional Neurosurgery, 2023, 36(2): 82-85.
[8]	Li Jingjun, Hu Wenhan, Zhang Chao, et al. Multimodal neuroimaging characteristics of tuberous sclerosis complex-related epilepsy [J]. Chinese Journal of Stereotactic and Functional Neurosurgery, 2023, 36(1): 17-21.
[9]	. [J]. Chinese Journal of Stereotactic and Functional Neurosurgery, 2022, 35(6): 377-381.
[10]	Ma Wei, Zhang Wei, Chen Long, et al. Electro-clinical characteristics and long-term surgical outcome of pseudotemporal lobe epilepsy [J]. Chinese Journal of Stereotactic and Functional Neurosurgery, 2022, 35(5): 269-272.
[11]	Lan Zhengbo, Han Yanming, Zhang Xinding, et al. supplementary motor area epilepsy surgery as demonstrated by SEEG:case report and review of the literature [J]. Chinese Journal of Stereotactic and Functional Neurosurgery, 2022, 35(5): 280-283.
[12]	. [J]. Chinese Journal of Stereotactic and Functional Neurosurgery, 2022, 35(5): 316-320.
[13]	Hu Jianfei,Zhou Junjian,Liu Yaoling,et al.. Application of Leksell frame stereotactic electroencephalography (L-SEEG) technique in locating insula and suspected insula epilepsy [J]. Chinese Journal of Stereotactic and Functional Neurosurgery, 2022, 35(4): 205-209.
[14]	Zhang Zhaozhao, Zhang Guangming, Liu YaoLing, et al. The significance of ELECTROencephalogram in cerebral hemispherectomy [J]. Chinese Journal of Stereotactic and Functional Neurosurgery, 2022, 35(3): 138-141.
[15]	Hou Xianchun, Wang Hong, Chang Yanjie, et al. Clinical study on seizure after spontaneous intracerebral hemorrhage in ICU and the application value of prophylactic antiseizure medications [J]. Chinese Journal of Stereotactic and Functional Neurosurgery, 2022, 35(3): 153-159.