The predictive value of preoperative MRI features for the recurrence risk of meningioma

doi:10.19854/j.cnki.1008-2425.2023.04.0007

Abstract

Abstract: Objective To investigate the predictive value of preoperative magnetic resonance imaging (MRI) features for postoperative recurrence of meningioma.Methods In this study,we analyzed the clinical data of 301 patients with meningioma who underwent surgery,and the correlation between tumor recurrence and imaging features (including tumor volume and peripheral edema,arachnoid integrity,tumor enhancement mode,capsule enhancement,T2 signal intensity,tumor shape,and calcification).Results High-grade histological pathology (OR,10.14;95% CI,5.65 to 18.22;P＜0.001),skull-base location (OR,0.49;95% CI,0.29 to 0.82;P=0.006),destruction of arachnoid integrity (OR,1.64;95% CI,1.02 to 2.62;P=0.039) and irregular shape (OR,1.92;95% CI,1.05 to 3.51;P=0.035),large tumor volume (OR,1.05;95% CI,1.03 to 1.08;P＜0.001) were associated with postoperative recurrence.Multivariate regression analysis showed high grade pathology (OR,10.52;95% CI,5.54 to 19.97;P＜0.001),large tumor volume (OR,1.04;95% CI,1.01 to 1.06;P=0.007) and disruption of arachnoid integrity (OR,2.14;95% CI,1.20 to 3.81;P=0.01) were independent predictors of tumor recurrence.Conclusion Preoperative MRI features such as tumor volume and arachnoid integrity can provide information on the risk of postoperative recurrence in patients with meningioma.

Key words: Meningioma, Recurrence, Tumor volume, Arachnoid integrity

摘要： 目的探讨脑膜瘤术前磁共振特征对术后复发的预测价值。方法回顾性分析了301名接受手术的脑膜瘤患者的临床资料及肿瘤体积和周围水肿、蛛网膜完整性、肿瘤强化方式、包膜强化、T2信号强度、肿瘤形状、钙化等影像学资料与肿瘤复发的相关性。结果高级别组织学病理 (OR,10.14;95%CI,5.65~18.22;P<0.001) 、颅底占位(OR,0.49;95%CI,0.29~0.82;P = 0.006)、蛛网膜完整性破坏 (OR,1.64;95%CI,1.02~2.62;P=0.039)、肿瘤形状不规则(OR,1.92;95%CI,1.05~3.51;P=0.035)、肿瘤体积较大(OR,1.05;95%CI,1.03~1.08;P< 0.001)与患者术后复发有关。多变量回归分析显示高级别病理 (OR,10.52;95%CI,5.54~19.97;P<0.001)、肿瘤体积较大(OR,1.04;95%CI,1.01~1.06;P=0.007)、蛛网膜完整性破坏(OR,2.14;95%CI,1.20~3.81;P=0.01)是肿瘤复发的独立预测因子。结论肿瘤体积及蛛网膜完整性等术前MRI特征可提供脑膜瘤患者术后复发风险相关信息。

关键词: 脑膜瘤, 复发, 肿瘤体积, 蛛网膜完整性

CLC Number:

R739.41

Jiang Yan, Zeng Yu, Liu BeI, et al. The predictive value of preoperative MRI features for the recurrence risk of meningioma[J]. Chinese Journal of Stereotactic and Functional Neurosurgery, 2023, 36(4): 228-232.

蒋艳, 曾煜, 刘备, 雷科. 脑膜瘤术前MRI特征对术后复发风险的预测价值研究[J]. 立体定向和功能性神经外科杂志, 2023, 36(4): 228-232.

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