doi:10.19854/j.cnki.1008-2425.2023.02.0012

Abstract

摘要： 目的探讨颅内动脉瘤破裂早期行血管内介入栓塞术对丙二醛(Malondialdehyde,MDA)、超氧化物歧化酶(Superoxide Dismutase,SOD)、D二聚体(D-Dimer,DD)水平的影响。方法以2018年5月~2021年6月在本院进行治疗的126例颅内动脉瘤破裂作为研究对象,根据手术时机不同分为早期组61例、延期组65例。观察两组治疗前后MDA、SOD、D-D水平,对比栓塞成功率、术中出血及术后并发症率。对两组均随访3个月(截止至2021年11月),评估患者近期预后。结果术后,两组MDA、D-D水平均下降,SOD水平升高,且早期组MDA、D-D水平低于延期组,SOD水平高于延期组(P<0.05);早期组栓塞成功率高于延期组(93.44% VS 81.45%)(P<0.05);早期组术后并发症总发生率低于延期组(6.56% VS 20.00%)(P<0.05);早期组近期预后良好占比高于延期组(81.97% VS 55.38%)(P<0.05)。结论颅内动脉瘤破裂患者早期行血管内介入栓塞术安全性较高,能改善MDA、SOD、D-D水平,提高栓塞成功率,患者近期预后较好。

关键词: 颅内动脉瘤, 破裂, 血管内介入栓塞术, MDA, SOD, D-D

CLC Number:

R739.4

于泓, 周林裕, 柏建斌. 颅内动脉瘤破裂早期行血管内介入栓塞术对MDA、SOD、D-D的影响[J]. 立体定向和功能性神经外科杂志, 2023, 36(2): 118-121.

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颅内动脉瘤破裂早期行血管内介入栓塞术对MDA、SOD、D-D的影响

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