Abstract: Objective To investigate the incidence, management, grading and related factors of the infection complications after cranial epilepsysurgery. Methods patients with epilepsywho underwent craniotomy were collected.Patients with the postoperative infection diagnosed bythe bacterial culture, clinical symptoms, and laboratory examinations were included in the study.The severity of the postoperative infection was graded according to the treatment.The factors related to the postoperative infection were analyzed. Results 26 patients with epilepsy had the postoperative infection, including 15 cases of central nervous system infection, 9 cases of wound infection and 2 cases of pulmonary infection.The overall incidenceof infectionafter surgery for epilepsy was 1.3%.The severity of postoperative infection was graded as follows:10 cases (38.5%) with grade 1, 3 cases (11.5%) with grade 2 and 13 cases (50%) with grade 3.There was statistical difference among the grades of infection (P<0.05).In the patients with postoperative fever, there were statistical differences in the postoperative hospital stay, previous history of craniotomy and hydrocephalus between the infected and non-infected groups (P<0.05). Conclusion Infection is a rare complication after cranial epilepsy surgery.Most of the postoperative infectionrequire surgical intervention.Patients with previous history of craniotomy are prone to the postoperative infection.

Key words: Epilepsy surgery, Craniotomy, Infection, Grade, Factor

摘要： 目的 探讨癫痫外科开颅术后感染并发症的发生率、处理、严重程度分级及相关因素分析。方法 收集癫痫外科开颅手术患者。通过细菌培养、临床症状及实验室检查确诊感染患者纳入研究。依据治疗方式对感染严重程进行分级。分析术后感染相关因素。结果 26例接受开颅手术的癫痫患者出现术后感染,其中中枢神经系统感染15例,切口感染9例和肺部感染2例。癫痫外科开颅术后总体感染率是1.3%。术后感染分级:1级10例(38.5%),2级3例(11.5%)和3级13例(50%)。不同类型感染的严重程度分级存在统计学差异(P＜0.05)。术后发热患者中,感染与无感染组在术后住院日、既往开颅史及合并脑积水方面存在统计学差异(P＜0.05)。结论 感染是癫痫外科开颅术后少见的并发症。多数需要外科干预治疗。既往开颅患者易于出现术后感染。

关键词: 癫痫外科, 开颅, 感染, 分级, 因素