Abstract: Objective To explore the impact of network process information construction of regional stroke center in Jiading District on the treatment time window and short-term prognosis of ischemic stroke. Methods A total of 245 intravenous thrombolytic patients treated in our department from January 2017 to December 2018 before the construction of network process informatization and 280 Intravenous thrombolysis patients treated in our department from January 2019 to December 2020 after the construction of network process informatization were collected to analyze the impact of network process informatization on Intravenous thrombolysis DNT(door to needle) and mRS after 90 days. Results The NIHSS score after thrombolysis .90 day mRS and DNT after network process informatization construction were significantly lower than those of The NIHSS score after thrombolysis .90 day mRS and DNT before network process informatization construction,and the difference was statistically significant. Conclusion Network process information construction can significantly shorten intravenous thrombolysis DNT and improve mRS after 90 days.

Key words: Regional stroke center, Network process information construction, Intravenous thrombolysis in ischemic stroke, DNT, mRS

摘要： 目的 探讨上海市嘉定区区域脑卒中中心网络流程信息化建设对缩短急性缺血性脑卒中(acute ischemic stroke,AIS)溶栓时间及短期预后的影响。方法 收集网络流程信息化建设前2017年1月～2018年12月我科收治的静脉溶栓患者共245例及网络流程信息化建设后2019年1月～2020年12月我科收治的静脉溶栓患者280例,分析网络流程信息化建设对静脉溶栓DNT(door to needle)及发病后90天mRS(modified rankin scale)的影响。结果 网络流程信息化建设后轻型、中度卒中DNT、溶栓后24小时、7天NIHSS评分及90天mRS较网络流程信息化建设前DNT、静脉溶栓后7天NIHSS评分及90天mRS明显降低,差异具有统计学意义;网络流程信息化建设后重型卒中DNT较网络流程信息化建设前明显缩短,但静脉溶栓后7天NIHSS评分及90天mRS无明显变化,差异无统计学意义。结论 网络流程信息化建设能显著缩短静脉溶栓DNT及改善轻型、中度卒中90天mRS,但重型卒中90天mRS无改善。

关键词: 区域卒中中心, 网络流程信息化建设, 缺血性脑卒中, 静脉溶栓, DNT, mRS