3D visualization technique assisted resection of limbic glioma by 3DSlicer

doi:10.19854/j.cnki.1008-2425.2024.02.0003

Abstract

Abstract: Objective To investigate the clinical value of 3DSlicer multi-modal fusion 3D visualization technology in assisting the surgical treatment of limbic system glioma. Methods The clinical data of 67 cases of limbic glioma treated in our hospital were retrospectively analyzed and divided into 32 cases of 3DSlicer reconstruction group(experimental group) and 35 cases of traditional operation group(control group) according to surgical methods.The differences of cognitive function(MMSE) score, Karnofsky performance status(KPS), tumor resection degree, complications and other clinical effects between the experimental group and the control group were analyzed. Results The MMSE score of cognitive function in the experimental group(28.50±2.20) was higher than that in the control group(25.40±4.972), P=0.002, the difference was significant.One month after operation, the KPS score of the experimental group(94.53±7.112) was higher than that of the control group(84.86±10.396), with significant difference(P＜0.001).The total resection rate of the experimental group was higher than that of the control group(Z=-3.271, P＜0.001).The complication rate of the control group was higher than that of the experimental group. Conclusion 3DSlicer multi-modal fusion 3D visualization technology can guide the surgical approach, maximize the safe resection of limbo system glioma, reduce postoperative cognitive and neurological dysfunction, reduce related complications, and increase the quality of life of patients.

Key words: Three-dimensional visualization, Glioma, Limbic system, Cognitive function, Complications

摘要： 目的探讨3DSlicer多模态融合三维可视化技术辅助切除边缘系统胶质瘤手术治疗的临床价值。方法回顾分析我院收治的67例边缘系统胶质瘤临床资料,按照手术方法分为3DSlicer重建组(实验组)32例和传统手术组(对照组)35例。分析实验组和对照组在认知功能(MMSE)评分及术后一月卡氏评分(Karnofsky performance status,KPS)、肿瘤切除程度、并发症等临床疗效的差异。结果术后实验组认知功能MMSE评分(28.50±2.20),高于对照组(25.40±4.972), P=0.002,差异显著;术后一月实验组KPS评分(94.53±7.112),高于对照组(84.86±10.396),P＜0.001,差异显著;实验组肿瘤全切除率高于对照组(Z=-3.271,P＜0.001);对照组并发症发生率高于实验组。结论 3DSlicer多模态融合三维可视化技术可以指导手术入路、最大化安全切除边缘系统胶质瘤,降低术后认知和神经功能障碍,减少相关并发症,增加患者生活质量。

关键词: 三维可视化, 胶质瘤, 边缘系统, 认知功能, 并发症

CLC Number:

P739.41

Liu Jiaji, Lu Xu, Li Dongxue. 3D visualization technique assisted resection of limbic glioma by 3DSlicer[J]. Chinese Journal of Stereotactic and Functional Neurosurgery, 2024, 37(2): 77-82.

刘家记, 卢旭, 李冬雪. 3DSlicer多模态融合三维可视化技术辅助切除边缘系统胶质瘤的临床效果和预后分析[J]. 立体定向和功能性神经外科杂志, 2024, 37(2): 77-82.

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