Abstract: Objective To investigate the predictive value of systemic inflammatory response markers on the degree of cerebral edema in patients with cerebral contusion.Methods The clinical data of 164 patients with non-surgical treatment of brain contusion admitted to our department from January 2020 to December 2022 were retrospectively analyzed.Results Among them,there were 62 patients with severe cerebral edema and 102 patients with mild to moderate cerebral edema.There were significant differences in systolic blood pressure,blood glucose concentration,white blood cell count,neutrophil-to-lymphocyte ratio,and platelet-to-lymphocyte ratio between the two groups on admission (P<0.05).Conclusion Blood glucose concentration and neutrophil-to-lymphocyte ratio at admission are independent risk factors affecting the degree of cerebral edema in patients with cerebral contusion.

Key words: Traumatic brain Injury, Brain edema, Systematic inflammatory factors, Blood brain barrier

摘要： 目的 研究系统性炎症反应标志物对脑挫伤患者脑水肿程度的预测价值。方法 回顾性分析2020年1月至2022年12月我科收治的164例非手术 治疗脑挫伤患者的临床资料。结果 其中有重度脑水肿患者62例,轻中度脑水肿患者102例。单因素分析两组患者间入院时收缩压、血糖浓度、白细胞计数、中性粒细胞比淋巴细胞比值、血小板比淋巴细胞比值有统计学差异(P＜0.05)。结论 入院时血糖浓度和中性粒细胞比淋巴细胞比值是影响脑挫伤患者脑水肿程度的独立危险因素。

关键词: 创伤性脑损伤, 脑水肿, 系统性炎性反应指标, 血脑屏障