关键词: 急性脑卒中, 孤立性下肢远端深静脉血栓, 危险因素

Abstract: Objective To investigate the risk factors of perioperative isolated deep vein thrombosis of the distal lower extremities in patients with acute stroke. Methods A retrospective analysis of the case data of acute stroke patients admitted to the First Affiliated Hospital of University of Science and Technology of China from September 2019 to May 2020,the patients were grouped according to the results of the dynamic ultrasound examination of the whole lower extremity veins,and multivariate logistics regression was applied.Analyze and determine the patient's age,gender,body mass index,admission GCS score,APACHE Ⅱ score,NICU stay time,whether there is brain hernia and shock,operation time,gastrointestinal hemorrhage,acute kidney injury,acute liver injury,blood transfusion and other factors and isolation The relationship between the occurrence of deep vein thrombosis in the distal lower limbs. Results A total of 105 patients with acute stroke were included,of which 83 were hemorrhagic stroke and 22 were ischemic stroke;71(68%) patients had isolated deep vein thrombosis of the distal lower extremities,and 57 cases(80%) were asymptomatic,12 cases(17%) developed thrombosis progression;univariate analysis showed that the patient's age(P=0.02),body mass index(P=0.009),admission GCS score(P=0.004),and red blood cell transfusion(P=0.035) were acute The risk factors of perioperative isolated deep vein thrombosis of the lower extremities in stroke patients.Multivariate logistic regression analysis showed that the patient's age was >60 years old(P=0.036,95%CI=1.068～7.458),and the admission GCS score was >8 Score(P=0.005,95%CI=0.087～0.641) and red blood cell transfusion(P=0.049,95%CI=0.44～0.932) are independent risk factors for the occurrence of deep vein thrombosis in the distal lower limbs. Conclusion The incidence and progression rate of isolated distal deep vein thrombosis in patients with acute stroke during the perioperative period are relatively high.Patient age,GCS score and blood transfusion are independent risk factors for thrombosis.For this type of patients,deep vein thrombosis of lower extremity should be strengthened,screening work.

Key words: Acute stroke, Isolated distal deep vein thrombosis, Risk factors