关键词: 顶叶癫痫, 脑电图, 痫样放电, 手术疗效

Abstract: Objective To investigate the characteristics of scalp EEG and relationship with surgical outcomein patients with lesional parietal lobe epilepsy (PLE).Methods We retrospectively analyzed the interictal and ictal scalp EEG of 53 lesional PLE patients admitted from January 2012 to December 2019who underwent resective surgical treatment,and compared the surgical outcome of patients with different EEG characteristics.Results In all53 patients,the distribution of interictal epileptiform discharges (IEDs) was:37.7% (20/53) had normal interictal EEG;17.0% (9/53) were distributed only in the lesional parietal lobe;the remaining 45.3% (24/53) were distributed beyond the lesional parietal lobe,of which 17.0% (9/53) were distributed only in the ipsilateraltemporal lobe.Of the 24 patients with captured clinical seizures,37.5% (9/24) had seizure origins in the lesional parietal lobe;62.5% (15/24) were uncertain or originated in other brain regions,of which 16.7% (4/24) originated in the ipsilateral temporal lobe.3 cases were lost to follow-up after surgery,and the remaining were followed up for a mean of 58.7 22.0 months.76.0% (38/50) of the patients were Engel class I.Due to the small number of cases,there was no statistical difference in surgical outcome between patients with different EEG characteristics (interictal or ictal) (all P>0.05).Conclusion The localization value of scalp EEG in patients with lesional PLE is low,and even somewhat misleading in localization,the localization value is greater in the ictal than in the interictal EEG,and there was no significant correlation between different EEG pattern and surgical outcome.

Key words: Parietal lobe epilepsy, EEG, Epileptiform discharges, Surgicaloutcomes