关键词: 癫痫外科, 开颅, 感染, 分级, 因素

Abstract: Objective To investigate the incidence, management, grading and related factors of the infection complications after cranial epilepsysurgery. Methods patients with epilepsywho underwent craniotomy were collected.Patients with the postoperative infection diagnosed bythe bacterial culture, clinical symptoms, and laboratory examinations were included in the study.The severity of the postoperative infection was graded according to the treatment.The factors related to the postoperative infection were analyzed. Results 26 patients with epilepsy had the postoperative infection, including 15 cases of central nervous system infection, 9 cases of wound infection and 2 cases of pulmonary infection.The overall incidenceof infectionafter surgery for epilepsy was 1.3%.The severity of postoperative infection was graded as follows:10 cases (38.5%) with grade 1, 3 cases (11.5%) with grade 2 and 13 cases (50%) with grade 3.There was statistical difference among the grades of infection (P<0.05).In the patients with postoperative fever, there were statistical differences in the postoperative hospital stay, previous history of craniotomy and hydrocephalus between the infected and non-infected groups (P<0.05). Conclusion Infection is a rare complication after cranial epilepsy surgery.Most of the postoperative infectionrequire surgical intervention.Patients with previous history of craniotomy are prone to the postoperative infection.

Key words: Epilepsy surgery, Craniotomy, Infection, Grade, Factor