基于表面形态学分析对颞叶内侧型癫痫手自动症的症状起始区定位

doi:10.19854/j.cnki.1008-2425.2022.02.0004

立体定向和功能性神经外科杂志 ›› 2022, Vol. 35 ›› Issue (2): 81-84.DOI: 10.19854/j.cnki.1008-2425.2022.02.0004

基于表面形态学分析对颞叶内侧型癫痫手自动症的症状起始区定位

李敬军, 王垚, 胡文瀚, 张弨, 王秀, 莫嘉杰, 邵晓秋, 张建国, 张凯

100072 北京北京市神经外科研究所(李敬军、胡文瀚);首都医科大学附属北京天坛医院神经外科(王垚、张弨、王秀、莫嘉杰、张建国、张凯),神经内科(邵晓秋)

收稿日期:2022-01-10 出版日期:2022-04-25 发布日期:2022-07-14
通讯作者: 张凯 zhangkai62035@163.com
基金资助:
国家自然科学基金面上项目(编号: 82071457);首都卫生发展科研专项项目(编号:首发2020-2-1076)

Symptomatogenic zone of hand automatisms in mesial temporal lobe epilepsy based on SBM analysis

Li Jingjun, Wang Yao, Hu Wenhan, et al

Beijing Neurosurgical Institute,Capital Medical University,Beijing,100072.China.2.Beijing Tiantan Hospital,Capital Medical University

Received:2022-01-10 Online:2022-04-25 Published:2022-07-14

摘要/Abstract

摘要： 目的探讨颞叶内侧型癫痫中手自动症的症状起始区。方法回顾性分析79例颞叶内侧型癫痫患者,根据是否存在手自动症以及手自动症累及单手还是双手分为三组,单侧手自动症组(HAU),双侧手自动症组(HAB)和无手自动症组(NH)。通过脑表面形态学分析的方法以皮质厚度为分析指标。三组病人分别和健康对照组作比较。结果 HAU和HAB两组皮质变薄区域都累及双侧的中央区、辅助运动区(SMA)和中扣带回(MCC)。NH组只发现双侧中央区受累。结论手自动症产生的症状起始区位于双侧SMA和MCC。单侧手自动症时对侧常合并肌张力障碍可能是导致单侧自动症组累及的脑区更加广泛的原因。

关键词: 颞叶癫痫, 表面形态学分析, 手自动症, 症状起始区

Abstract: Objective To explore the symptomatogenic zone of hand automatisms in mesial temporal lobe epilepsy. Methods Seventy-nine patients with mesial temporal lobe epilepsy were retrospectively analyzed.According to the occurrence of hand automatism and involved side,they were divided into three groups:unilateral hand automatism group (HAU),bilateral hand automatism group (HAB) and no hand automatism group (NH).The cortical thickness based on surface-based morphometry (SBM) was used for analysis.Three groups of patients were compared with healthy control group. Results In both HAU and HAB groups,bilateral Rolandic area,supplementary motor area (SMA) and middle cingulate gyrus (MCC) were involved.In NH group,only bilateral Rolandic area involvement was found. Conclusion The symptomatogenic zone of hand automatism is located in bilateral SMA and MCC.Dystonia often occurs in the contralateral side of unilateral automatism,which may be the reason for more extensive brain involvement in unilateral automatism.

Key words: Temporal lobe epilepsy, Surface morphology analysis, Hand automatism, Symptomatogenic zone

中图分类号:

R742.1

李敬军, 王垚, 胡文瀚, 张弨, 王秀, 莫嘉杰, 邵晓秋, 张建国, 张凯. 基于表面形态学分析对颞叶内侧型癫痫手自动症的症状起始区定位[J]. 立体定向和功能性神经外科杂志, 2022, 35(2): 81-84.

Li Jingjun, Wang Yao, Hu Wenhan, et al. Symptomatogenic zone of hand automatisms in mesial temporal lobe epilepsy based on SBM analysis[J]. Chinese Journal of Stereotactic and Functional Neurosurgery, 2022, 35(2): 81-84.

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基于表面形态学分析对颞叶内侧型癫痫手自动症的症状起始区定位

Symptomatogenic zone of hand automatisms in mesial temporal lobe epilepsy based on SBM analysis

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