关键词: 术中超声, 脑深部肿瘤, 手术入路

Abstract: Objective To assess diagnostic performance of the intraoperative ultrasonography in neuro-oncology practice based on the clinical features of patients with deep-seated brain tumors.Methods A retrospective review of 24 patients who were treated for deeply seated brain tumors has been performed.Among these cases,13 patients underwent tumor resection via dissection of the non-eloquent cortex or trans-sulcal approach depending on the intraoperative ultrasonic findings (ultrasound-guided group),while 11 patients experienced trans-sulcal approach without intraoperative ultrasonography (control group).Data regarding clinical findings and technical considerations were analyzed.Results No statistically significant difference was observed in the age,tumor diameter,depth of the lesions,and preoperative Karnofsky Performance Scale (KPS) of these 2 groups.However,shorter exposure time,less microscopic or endoscopic procedure time,reduced duration of hospitalization,a fewer extent of focal encephalomalacia,and higherKPS 3 months after surgery were all achieved statistical significance in patients in the ultrasound-guided group when compared with the control group (P＜0.05).Moreover,the ultrasound-guided surgery provided higher rate of gross total resection,fewer complications,and less degree of postoperative brain edema.Conclusion Intraoperative ultrasonography can accurately identify deeply seated brain tumors,andmay compensate for craniotomy-induced brain-shift.Shortening operation duration,complete tumor resection with minimal invasion,and improved recovery time can be obtained via the ultrasonic-guided surgery,resulting insurvival benefits.

Key words: Intraoperative ultrasonography, Deep-seated brain tumors, Surgical approach